Structural compatibility enables functional co-assembly of Kir2.1 channels and the voltage-sensing domain of voltage-sensitive phosphatases
Anagha Gopalakrishnan Nair, Philipp Rühl, Lina Seeber, Toshinori Hoshi, Roland Schoenherr, Stefan H. Heinemann
This study shows that Kir2.1 channels and voltage-sensing domains can co-assemble into functional KV-like complexes, altering voltage-dependent fluorescence responses.
bioRxiv · Aug 7, 2026 · PreprintPhysiology