Linda Zhou

Polygenic Risk Scores for Kidney Function to the Circulating Proteome, and Incident Kidney Diseases: the Atherosclerosis Risk in Communities Study

This study develops a polygenic risk score for eGFR and shows its association with kidney disease outcomes and plasma proteins in the ARIC study.

Consequences of PCA graphs, SNP codings, and PCA variants for elucidating population structure

The paper evaluates common misuses of PCA in SNP data analysis and recommends best practices for improving population structure elucidation.