Author

Jingsha Chen

Johns Hopkins University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Assay:GWAS summary statistics· 1 Assay:imaging· 1 Approach:machine learning (classical)· 1 Research Focus:polygenic risk· 1 Assay:proteomics· 1

Frequent Co-Authors

Josef CoreshiD· 2 shared Aditya SurapaneniiD· 1 shared Adrienne TiniD· 1 shared Alexander J. EhrenbergiD· 1 shared Alexandra N. TrelleiD· 1 shared Amelia FarinasiD· 1 shared Anna KöttgeniD· 1 shared Anssi LipponeniD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersNeuroscience

Josef CoreshORCID

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2 papers

Recent·Most cited

Synapse protein signatures in cerebrospinal fluid and plasma predict cognitive maintenance versus decline in Alzheimers disease

Hamilton Se‐Hwee Oh, Deniz Yagmur Urey, Linda Karlsson, Zeyu Zhu, Yuanyuan Shen, Amelia Farinas, Jigyasha Timsina, Michael R. Duggan, Jingsha Chen, Ian Hunter Guldner, Nader Morshed, Chengran Yang, Daniel Western, Muhammad Ali, Yann Le Guen, , Tony Wyss‐Coray

CSF YWHAG:NPTX2 synapse protein ratio, from proteomics of 3,416 individuals across six cohorts, explains cognitive impairment beyond amyloid and tau and predicts decline (hazard ratio 15.4).

Nature Medicine · Mar 31, 2025Peer-reviewedNeuroscience✦ In-depth digest

Polygenic Risk Scores for Kidney Function to the Circulating Proteome, and Incident Kidney Diseases: the Atherosclerosis Risk in Communities Study

Zhi Yu, Jin Jin, Adrienne Tin, Anna Köttgen, Bing Yu, Jingsha Chen, Aditya Surapaneni, Linda Zhou, Christie Mitchell Ballantyne, Ron Cornelis Hoogeveen, Dan E. Arking, Nilanjan Chatterjee, Morgan Erika Grams, Josef Coresh

This study develops a polygenic risk score for eGFR and shows its association with kidney disease outcomes and plasma proteins in the ARIC study.

bioRxiv · Sep 5, 2020 · PreprintGenetics