Spatial Transcriptomics Identifies Immune-Stromal Niches Associated with Cancer in Adult Dermatomyositis
Ksenia S. Anufrieva, Neda Shahriari, Ce Gao, Stephanie Pei Tung Yiu, Shideh Kazerounian, Rochelle L. Castillo, Jessica Liu, Sean A. Prell, Kartik Bhamidipati, Khashayar Afshari, Lindsay Parmelee, Anastasia N. Kazakova, Erin Theisen, Teresa Venezia Bowman, Avery LaChance, , Kevin Wei
This study uses spatial and single-cell transcriptomics to identify immune-stromal niches in adult-onset dermatomyositis, revealing distinct cellular and cytokine signatures associated with cancer and non-cancer lesions.
Nature Communications · Jun 26, 2026Peer-reviewedImmunology