Stephanie Pei Tung Yiu

This study uses spatial and single-cell transcriptomics to identify immune-stromal niches in adult-onset dermatomyositis, revealing distinct cellular and cytokine signatures associated with cancer and non-cancer lesions.

This study uses spatial multi-omics to compare EBV-positive and EBV-negative cHL, identifying distinct TME features and immunological signatures linked to EBV.

COSIE is a computational framework that integrates multiple spatial omics modalities to generate high-resolution molecular landscapes, outperforming existing methods across diverse datasets.

The paper introduces two methods to profile functional glycan-lectin interactions in tissues using single-cell and spatial multiomic approaches, revealing stimulus-specific glycan remodeling and spatial glycan programs in immune cells and follicular lymphoma.

PASTA enhances spatial biology detection sensitivity while maintaining compatibility with multiple modalities and multiplexing strategies.

This paper introduces IN-DEPTH and SGCC for spatial multi-omics analysis, revealing EBV-related immunomodulatory differences in DLBCL.