Spatiotemporal proteomic profiling of genome editing-associated microenvironment
Siqi Xi, Linghao Kong, Weijie Zhou, Xuan Liang, Peng R. Chen, Xinyuan Fan
This study develops a Cas9-TurboID platform to map dynamic protein assemblies around genome editing sites and identifies factors that enhance editing efficiency in heterochromatic regions.
bioRxiv · Oct 26, 2026 · PreprintCell Biology