Peng R. Chen

This study develops a Cas9-TurboID platform to map dynamic protein assemblies around genome editing sites and identifies factors that enhance editing efficiency in heterochromatic regions.

This paper introduces Gentle Rhodamines with reduced phototoxicity for live-cell imaging, enabling time-lapse and voltage imaging with less cellular damage.

This paper develops a system to package mRNAs into AAVs, enabling efficient whole-brain mRNA delivery in mice.

This study identifies calcineurin as a phosphatase that dephosphorylates SIK3 at specific sites, linking it to sleep regulation in mice.