Regeneration of spinal motor axons: Negative regulation by Celsr2 implicating Cdc42/Rac1 and JNK/c-Jun signaling
Quan Wen, Huandi Weng, Tao Liu, Lingtai Yu, Tainyun Zhao, Jingwen Qin, Fadel Tissir, Yibo Qu, Libing Zhou
This study shows that Celsr2 negatively regulates motor axon regeneration in mice and humans, with its knockdown promoting axon regeneration and functional recovery.
bioRxiv · Jan 20, 2021 · PreprintNeuroscience