CXXC-finger protein 1 associates with FOXP3 to stabilize homeostasis and suppressive functions of regulatory T cells
Xiaoyu Meng, Yezhang Zhu, Kuai Liu, Yuxi Wang, Xiaoqian Liu, Chenxin Liu, Yan Jun Zeng, Shuai Wang, Xianzhi Gao, Xin Shen, Jing Chen, Sijue Tao, Qianying Xu, Linjia Dong, Li Shen, Lie Wang
This study shows that CXXC1 interacts with FOXP3 to regulate Treg cell function and epigenetic stability, essential for immune homeostasis and preventing inflammation.
bioRxiv · Sep 30, 2024Immunology