Author

Linxi Cheng

Chinese Academy of Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Yuhua SuniD· 3 shared Xiaoyun SuniD· 2 shared Bei TongiD· 1 shared Kai HuangiD· 1 shared Lin WangiD· 1 shared Minghui XieiD· 1 shared Nianguo DongiD· 1 shared Tianzhe ZhangiD· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersDevelopmental Biology

Yuhua SunORCID

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3 papers

Recent·Most cited

POGZ suppresses 2C transcriptional program and retrotransposable elements

Xiaoyun Sun, Tianzhe Zhang, Bei Tong, Linxi Cheng, Wei Jiang, Yuhua Sun

This study shows that POGZ maintains ESCs by repressing Dux and silencing ERVs, leading to genome instability when POGZ is depleted.

Cell Reports · Jan 1, 2022Peer-reviewedMolecular Biology

Generation of cardiac valve endocardial like cells from human pluripotent stem cells

Linxi Cheng, Minghui Xie, Weihua Qiao, Yu Song, YanYong Zhang, YingChao Geng, Weilin Xu, Lin Wang, Zheng Wang, Kai Huang, Nianguo Dong, Yuhua Sun

This paper describes a method to generate valve endocardial progenitor cells from human pluripotent stem cells and shows they resemble primary valve endothelial cells.

Communications Biology · Sep 6, 2021Peer-reviewedDevelopmental Biology

POGZ controls embryonic stem cell self-renewal and pluripotency by association with esBAF and HP1

Xiaoyun Sun, Linxi Cheng, Yuhua Sun

This study identifies POGZ as a critical factor for maintaining embryonic stem cell pluripotency by interacting with esBAF and HP1, and shows its role in chromatin regulation and transcriptional circuitry.

bioRxiv · Feb 7, 2021 · PreprintDevelopmental Biology