Author

Xiaoyun Sun

Chinese Academy of SciencesORCID 0000-0001-7118-5231Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1

Frequent Co-Authors

Yuhua SuniD· 3 shared Linxi Cheng· 2 shared Bei TongiD· 1 shared Tianzhe ZhangiD· 1 shared Wei JiangiD· 1 shared Xixia PengiD· 1 shared Yan ZhouiD· 1 shared Yuqin CaoiD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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3 shared papersDevelopmental Biology

Yuhua SunORCID

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3 papers

Recent·Most cited

Molecular BiologyCell ReportsPeer-reviewedJan 1, 2022

POGZ suppresses 2C transcriptional program and retrotransposable elements

Xiaoyun Sun, Tianzhe Zhang, Bei Tong…·Yuhua Sun

This study shows that POGZ maintains ESCs by repressing Dux and silencing ERVs, leading to genome instability when POGZ is depleted.

21 citations

mousebulk RNA-seq

𝕏 PostBluesky

Developmental BiologybioRxivPreprintFeb 7, 2021

POGZ controls embryonic stem cell self-renewal and pluripotency by association with esBAF and HP1

Xiaoyun Sun, Linxi Cheng, Yuhua Sun

This study identifies POGZ as a critical factor for maintaining embryonic stem cell pluripotency by interacting with esBAF and HP1, and shows its role in chromatin regulation and transcriptional circuitry.

DOI 10.1101/2021.02.07.430173

mousebulk RNA-seq

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Developmental BiologyNature CommunicationsPeer-reviewedJun 12, 2020

ADNP promotes neural differentiation by modulating Wnt/β-catenin signaling

Xiaoyun Sun, Xixia Peng, Yuqin Cao…·Yuhua Sun

This study shows ADNP is essential for neural differentiation by maintaining Wnt/β-catenin signaling, and its disruption causes neural developmental defects in mice and zebrafish.

108 citations

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