Yuhua Sun

Trpv4 links environmental temperature to testicular differentiation in hermaphroditic ricefield eel

This study shows that Trpv4 links environmental temperature to testicular differentiation in ricefield eel by regulating the Trpv4-pStat3-Kdm6b-dmrt1 pathway.

Circadian control of kidney regeneration via Lima1-mediated regulation of EMT

This study investigates the role of circadian clock genes in kidney regeneration using zebrafish, finding that per1 and nr1d1 promote regeneration by repressing lima1a, which regulates EMT.

POGZ suppresses 2C transcriptional program and retrotransposable elements

This study shows that POGZ maintains ESCs by repressing Dux and silencing ERVs, leading to genome instability when POGZ is depleted.

Generation of cardiac valve endocardial like cells from human pluripotent stem cells

This paper describes a method to generate valve endocardial progenitor cells from human pluripotent stem cells and shows they resemble primary valve endothelial cells.

POGZ controls embryonic stem cell self-renewal and pluripotency by association with esBAF and HP1

This study identifies POGZ as a critical factor for maintaining embryonic stem cell pluripotency by interacting with esBAF and HP1, and shows its role in chromatin regulation and transcriptional circuitry.

ADNP promotes neural differentiation by modulating Wnt/β-catenin signaling

This study shows ADNP is essential for neural differentiation by maintaining Wnt/β-catenin signaling, and its disruption causes neural developmental defects in mice and zebrafish.