N-Terminal Alkylation of Proteins with Triazole-4-carbaldehyde for Targeted Liposome Engineering
Lisa Connolly, Akimitsu Okamoto, Neal K. Devaraj, Akira Onoda
This paper develops a method to attach proteins to liposomes via N-terminal alkylation using TA4C, enabling targeted delivery to EGFR-overexpressing cells.
bioRxiv · Aug 3, 2026 · PreprintBiochemistry