Predicting Personalised Therapeutic Combinations in Non-Small Cell Lung Cancer Using In Silico Modelling
Matthew A. Clarke, Charlie George Barker, Ashley Nicholls, Matt P. Handler, Lisa Pickard, Amna Z. Shah, David Walter, Etienne D. Braekeleer, Udai Banerji, Jyoti Sharma Choudhary, Saif Ahmed, Ultan McDermott, Gregory J. Hannon, Jasmin Fisher
This paper develops an in silico model to predict personalized therapeutic combinations for NSCLC by simulating genetic profiles and testing drug combinations to overcome resistance.
bioRxiv · Jan 7, 2025 · PreprintCancer Biology