Lineage-associated tumor cell states predict outcome and guide immunotherapeutic target selection in pediatric osteosarcoma
Lindy L. Visser, Stephanie A Schubert, Baojie Zhang, Lisa Vork Jansen, Irene F. Gosselink, Georgios Karakatsoulis, Jeff DeMartino, Laura S. Hiemcke‐Jiwa, Johannes H. M. Merks, Thanasis Margaritis, Claudia Y. Janda
This study identifies lineage-associated tumor cell states in pediatric osteosarcoma that correlate with clinical outcomes and guide immunotherapeutic target selection.
bioRxiv · Jun 16, 2026 · PreprintCancer Biology