α-Synuclein pathology in Parkinson disease activates homeostatic NRF2 anti-oxidant response
Alberto Delaidelli, Mette Richner, Lixiang Jiang, Amelia van der Laan, Ida Bergholdt Jul Christiansen, Nelson Ferreira, Jens Randel Nyengaard, Christian Bjerggaard Vægter, Poul Henning Jensen, Ian R. Mackenzie, Poul H. B. Sorensen, Asad Jan
The paper shows that α-synuclein pathology in Parkinson's disease activates the NRF2 anti-oxidant response, suggesting it could be a therapeutic target.
Acta Neuropathologica Communications · Jun 6, 2021Peer-reviewedNeuroscience