Author

Asad Jan

Aarhus UniversityORCID 0000-0002-3636-0070Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Jens Randel NyengaardiD· 4 shared Christian Bjerggaard VægteriD· 3 shared Mette RichneriD· 3 shared Poul Henning JenseniD· 3 shared Alberto DelaidelliiD· 2 shared Diana Gomes MoreiraiD· 2 shared Ian R. MackenzieiD· 2 shared Islam Mustafa Galal FaressiD· 2 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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4 shared papersNeuroscience

Jens Randel NyengaardORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

NeuroscienceeLifePeer-reviewedSep 22, 2026

Pathogenic O-GlcNAc dyshomeostasis associated with cortical malformations and hyperactivity

Florence Authier, Asad Jan, Islam Mustafa Galal Faress…·Daan M. F. van Aalten

This study investigates a rodent model with an OGT-ID variant, revealing neurodevelopmental defects and behavioural abnormalities linked to O-GlcNAc dyshomeostasis.

DOI 10.7554/elife.107170.3

mousestatistical model

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NeurosciencebioRxivPreprintSep 27, 2024

Molecular signatures of altered energy metabolism and circadian rhythm perturbations in a model of extra-nigral Synucleinopathy.

Lin Lin, Nanna Møller Jensen, Sara Almeida Ferreira…·Asad Jan

This study uses spatial transcriptomics to analyze aSyn pathology in mice, revealing metabolic and circadian disruptions at different stages of disease progression.

DOI 10.1101/2024.09.27.615378

mousespatial transcriptomics

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NeurosciencebioRxivPreprintSep 5, 2024

Bradykinesia and postural instability in a model of prodromal Synucleinopathy with alpha-Synuclein aggregation in the gigantocellular nuclei.

Vasileios Theologidis, Sara Almeida Ferreira, Nanna Møller Jensen…·Asad Jan

This study induces alpha-Synuclein aggregation in the gigantocellular nuclei of transgenic mice to model prodromal Parkinson's disease and observe motor symptom progression.

1 citation

mouseexperimental assay

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NeuroscienceActa Neuropathologica CommunicationsPeer-reviewedJun 6, 2021

α-Synuclein pathology in Parkinson disease activates homeostatic NRF2 anti-oxidant response

Alberto Delaidelli, Mette Richner, Lixiang Jiang…·Asad Jan

The paper shows that α-synuclein pathology in Parkinson's disease activates the NRF2 anti-oxidant response, suggesting it could be a therapeutic target.

39 citations

humanbulk RNA-seq

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