Author

Lixiao Che

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Molecular Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Camille K. Stevenson· 1 shared Chunying DuiD· 1 shared David R. PlasiD· 1 shared Jiang WangiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperMolecular Biology

Camille K. Stevenson

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1 paper

Recent·Most cited

BRUCE liver-deficiency potentiates MASLD/MASH in PTEN liver-deficient background by impairment of mitochondrial metabolism in hepatocytes and activation of STAT3 signaling in hepatic stellate cells

Lixiao Che, Camille K. Stevenson, David R. Plas, Jiang Wang, Chunying Du

The paper shows BRUCE and PTEN together suppress MASLD/MASH by maintaining mitochondrial metabolism and preventing STAT3 activation in HSCs, with DKO mice showing severe liver disease.

bioRxiv · Sep 13, 2024 · PreprintMolecular Biology