Author

Liyong He

State Key Laboratory of Digital Medical Engineering

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:long-read sequencing· 1

Frequent Co-Authors

Handong WangiD· 2 shared Jiahao SheniD· 2 shared Kaiqiang Ye· 2 shared Wenyi ZhangiD· 2 shared Xiangwei ZhaoiD· 2 shared Yan HuangiD· 2 shared Aiqun Chen· 1 shared Dongmei Zhang· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersGenomics

Handong WangORCID

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Author profile →

2 papers

Recent·Most cited

Ultra-fast and scalable high-resolution full-length single-cell RNA sequencing using CHART-seq

Wenyi Zhang, Aiqun Chen, Kaiqiang Ye, Handong Wang, Jiahao Shen, Zhe Jiao, Yunxia Guo, Yiming Xu, Dongmei Zhang, Yan Huang, Liyong He, Xiaofei Gao, Xiangwei Zhao

CHART-seq enables ultra-fast, scalable full-length single-cell RNA sequencing with improved gene detection and isoform annotation compared to existing methods.

bioRxiv · Sep 24, 2026 · PreprintGenomics

Unbiased Single-Cell Transcriptome-Proteome Co-Profiling Reveals Malignant Dormancy and Post-Transcriptional Buffering of CTCs

Liyong He, Kaiqiang Ye, Huiying Li, Lin Jiang, Wenyi Zhang, Kaitong Dang, Xiaoying Ma, Jiahao Shen, Yuwei Dong, Wenjia Wang, Handong Wang, Zhen‐Li Huang, Yan Huang, Nan Xiang, Zhenyu Yin, Xiangwei Zhao

The paper develops a method to co-profile transcriptomes and proteomes of rare CSF-CTCs, revealing malignant dormancy and post-transcriptional buffering as key mechanisms of treatment resistance.

bioRxiv · Mar 18, 2026 · PreprintCell Biology