Unbiased Single-Cell Transcriptome-Proteome Co-Profiling Reveals Malignant Dormancy and Post-Transcriptional Buffering of CTCs
Liyong He, Kaiqiang Ye, Huiying Li…·Xiangwei Zhao
The paper develops a method to co-profile transcriptomes and proteomes of rare CSF-CTCs, revealing malignant dormancy and post-transcriptional buffering as key mechanisms of treatment resistance.