Beyond The Linear Genome: Comprehensive Determination Of The Endogenous Circular Elements In C. elegans And Human Genomes Via An Unbiased Genomic-Biophysical Method
Massa J. Shoura, Idan Gabdank, Loren L Hansen, Jason D. Merker, Jason R. Gotlib, Stephen D. Levene, Andrew Z. Fire
The paper identifies and characterizes endogenous circular DNA (eccDNA) in C. elegans and human cells using unbiased methods, showing eccDNA originates from both coding and noncoding regions.
G3 Genes Genomes Genetics · Aug 11, 2017Peer-reviewedGenomics