Library-based single-cell analysis of CAR signaling reveals drivers of in vivo persistence
Caleb R. Perez, Andrea Garmilla, Avlant Nilsson, Hratch Baghdassarian, Khloe S. Gordon, Louise G. Lima, Blake E. Smith, Marcela Valderrama Maus, Douglas A. Lauffenburger, Michael E. Birnbaum
The paper uses single-cell sequencing to analyze CAR signaling and identifies ICD architectures that promote durable in vivo persistence in liquid tumors.
Cell Systems · May 2, 2024Peer-reviewedImmunology