Epigenetic Crosstalk Between BCG-Infected Macrophages and Naive Monocytes Potentiates Antimycobacterial Activity
Lovisa Ellinger, Shamila D. Alipoor, Shumaila Sayyab, Sadaf Kalsum, Maria Lerm
This study shows that BCG-infected macrophages release EVs that epigenetically reprogram naive monocytes, enhancing their antimycobacterial activity against Mtb.
bioRxiv · Jan 12, 2026 · PreprintMolecular Biology