Maria Lerm

Epigenetic Crosstalk Between BCG-Infected Macrophages and Naive Monocytes Potentiates Antimycobacterial Activity

This study shows that BCG-infected macrophages release EVs that epigenetically reprogram naive monocytes, enhancing their antimycobacterial activity against Mtb.

System-level health profiling from blood DNA methylation with explainable deep learning

The paper develops an explainable deep learning framework to predict health scores from blood DNA methylation, showing strong predictive accuracy and alignment with biological processes.

DNA methylome-based validation of induced sputum as an effective protocol to study lung immunity: construction of a classifier of pulmonary cell types

The paper validates sputum induction as a method to study lung immunity using DNA methylation signatures and develops a classifier for pulmonary cell types.