Genetic analysis of blood molecular phenotypes reveals regulatory networks affecting complex traits: a DIRECT study.
Andrew Anand Brown, Juan J. Fernandez-Tajes, Mun‐Gwan Hong, Caroline Brorsson, Robert Wilhelm Koivula, David Davtian, Théo Dupuis, Ambra Sartori, Theodora-Dafni Michalettou, Ian M. Forgie, Jonathan Adam, Kristine Højgaard Allin, Robert J. Caiazzo, Henna Cederberg, Federico De Masi, , Ulrik Plesner Jacobsen
The paper identifies shared genetic regulation across mRNA, proteins, and metabolites in blood, revealing networks and mediators of GWAS variants.
Nature Communications · Aug 21, 2023Peer-reviewedGenetic & Genomic Medicine