Author

Théo Dupuis

University of DundeeORCID 0000-0002-5057-6222Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Research Focus:GWAS / association mapping· 2 Research Focus:eQTL / molecular QTL mapping· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrew Anand BrowniD· 3 shared Adem Y. DawediD· 2 shared Ambra Sartori· 2 shared David DavtianiD· 2 shared Adriaan van der GraafiD· 1 shared Aiman Farzeen· 1 shared Alaa’ Lufti MelhemiD· 1 shared Alasdair TayloriD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersGenetic & Genomic Medicine

Andrew Anand BrownORCID

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3 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintFeb 5, 2026

Trans-eQTLs reveal the architecture of human gene regulatory networks

Robert Warmerdam, Harm-Jan Westra, Adriaan van der Graaf…·Habibul Ahsan

The paper maps cis- and trans-eQTLs in blood samples to infer gene regulatory networks and prioritize trait-relevant pathways.

2 citations

humanbulk RNA-seq

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Genetic & Genomic MedicineNature CommunicationsPeer-reviewedAug 21, 2023

Genetic analysis of blood molecular phenotypes reveals regulatory networks affecting complex traits: a DIRECT study.

Andrew Anand Brown, Juan J. Fernandez-Tajes, Mun‐Gwan Hong…·Ulrik Plesner Jacobsen

The paper identifies shared genetic regulation across mRNA, proteins, and metabolites in blood, revealing networks and mediators of GWAS variants.

44 citationstop 2%

humanbulk RNA-seq

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Genetic & Genomic MedicinemedRxivPreprintMay 4, 2023

XBP1 expression in pancreatic islet cells is associated with poor glycaemic control across ancestries especially in young non-obese onset diabetes

Théo Dupuis, Ranjit Mohan Anjana, Sundararajan Srinivasan…·Moneeza Kalhan Siddiqui

This study identifies XBP1 expression in pancreatic islets as a genetic factor associated with poor glycaemic control and increased T2DM risk in South and East Asians, particularly in young non-obese onset diabetes.

DOI 10.1101/2023.05.04.23289501

humanbulk RNA-seq

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