Functional mapping of N-terminal residues in the yeast proteome uncovers novel determinants for mitochondrial protein import.
Salomé Nashed, Houssam El Barbry, Médine Benchouaia, Angélie Dijoux-Maréchal, Thierry Delaveau, Nadia Ruiz-Gutierrez, Lucie Gaulier, Déborah Tribouillard‐Tanvier, Guillaume Chevreux, Stéphane Le Crom, Benoı̂t Palancade, Frédéric Devaux, Élodie Laine, Mathilde Garcia
The paper identifies N-terminal signatures in yeast proteins that influence mitochondrial import, showing hydrophobic residues at position 2 are critical and conserved across Saccharomycotina yeasts.
PLoS Genetics · Aug 16, 2023Peer-reviewedGenomics