Activity-assembled nBAF complex mediates rapid immediate early gene transcription by regulating RNA Polymerase II productive elongation.
Karen G. Cornejo, Andie Venegas, Morgan H. Sono, Madeline Door, Brenda Gutierrez-Ruiz, Lucy B. Karabedian, Supratik G. Nandi, Marco Hadisurya, W. Andy Tao, Emily C. Dykhuizen, Ramendra N. Saha
This study shows the nBAF complex facilitates activity-induced transcription of IEGs by regulating RNA Polymerase II elongation through its assembly and ATPase activity.
Cell Reports · Oct 15, 2024Peer-reviewedNeuroscience