Crystal structures of SARS-CoV-2 ADP-ribose phosphatase (ADRP): from the apo form to ligand complexes
K. Michalska, Youngchang Kim, Robert P. Jedrzejczak, Natalia I. Maltseva, Lucy M. Stols, Michael J Endres, A. Joachimiak
The paper determines crystal structures of SARS-CoV-2 ADRP and shows conformational changes upon ligand binding, identifying a conserved water molecule involved in hydrolysis.
IUCrJ · Jul 17, 2020Peer-reviewedMolecular Biology