Axon demyelination and degeneration in a zebrafishspastizin model of hereditary spastic paraplegia
Vranda Garg, Selina André, Luisa Heyer, Gudrun Kracht, Torben Ruhwedel, Patricia Scholz, Till Ischebeck, Hauke B. Werner, Christian Dullin, Jacob Engelmann, Wiebke Möbius, Martin C. Göpfert, Roland Dosch, Bart R. H. Geurten
This study investigates the effects of spastizin mutations in zebrafish, showing axon demyelination and degeneration in M-cells, leading to impaired locomotion.
Open Biology · Nov 1, 2024Peer-reviewedNeuroscience