Targeting COL4A1-Related Small Vessel Disease: Repurposed Pharmacotherapies for Genetic Vasculopathies
Klaudia Kocsy, H. Scott Wilkinson, Zuzanna Sokolowska, Luke F Bolger, Vedanth Kumar, Yan An, Favour Felix-Ilemhenbhio, Alisdair McNeill, Sanjay R. Jain, Tom Van Agtmael, Mimoun Azzouz, Arshad Majid
This paper identifies repurposed drugs that improve endothelial function in COL4A1-related disorders using in vitro and in vivo models.
bioRxiv · May 11, 2026 · PreprintMolecular Biology