Molecular BiologybioRxivPreprint
Cell-type specialization in the brain is encoded by specific long-range chromatin topologies
Warren Winick‐Ng, Alexander Kukalev, Izabela Harabula…·Ana Pombo
The paper investigates cell-type specific 3D chromatin structures in the brain using immunoGAM, finding TAD melting, neuron-specific contacts, and compartmentalization patterns related to gene expression and neurodegenerative diseases.