Chemical imaging unveils mitochondria as the major site of medicinal biguanide accumulation within cells
Lei Wang, Xianrong Zeng, Yanjie Li, Wanyu Hao, Zijing Yu, Luxia Yao, Yongdeng Zhang, Zhaobin Wang, Lianfeng Wu
This study uses chemical imaging to show that metformin accumulates primarily in mitochondria within cells.
Heliyon · Jul 1, 2024Peer-reviewedMolecular Biology