Author

Yongdeng Zhang

Westlake UniversityORCID 0000-0002-4569-8137Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Approach:microscopy & imaging analysis· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Abhijith RadhakrishnaniD· 1 shared Hong Joo KimiD· 1 shared Hong ZhengiD· 1 shared J. Paul TayloriD· 1 shared James Edward RothmaniD· 1 shared Jean N. D. Goder· 1 shared Jeff ColemaniD· 1 shared Jiang DuiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCell Biology

Abhijith RadhakrishnanORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Alphaviral nonstructural protein-host RBP co-condensation as a mechanism to sustain virus replication

Yi Liu, Zhiying Yao, Yun Zhang, Zhenshuo Zhu, Ziqiu Wang, Qi Chen, Zemin Yang, Yexuan He, Xiaoxin Chen, Le Tian, Jiang Du, Jinjun Wu, Hong Joo Kim, Jing Huang, Yongdeng Zhang, , Peiguo Yang

This study identifies nsP3-RBP co-condensation as a mechanism alphaviruses use to sustain replication, showing disruption of these condensates can inhibit viral replication.

Molecular Cell · May 21, 2026Peer-reviewedCell Biology

The Golgi Rim is a Precise Tetraplex of Golgin Proteins that Can Self-Assemble into Filamentous Bands

Maohan Su, Abhijith Radhakrishnan, You Yan, Yuan Tian, Hong Zheng, Ons M’Saad, Morven M. Graham, Jeff Coleman, Jean N. D. Goder, Xinran Liu, Yongdeng Zhang, Joerg Bewersdorf, James Edward Rothman

The paper uses super-resolution microscopy to show golgin proteins form a tetraplex at the Golgi rim and self-assemble into filamentous bands, proposing a model for Golgi stack formation.

bioRxiv · Mar 27, 2025 · PreprintCell Biology

Chemical imaging unveils mitochondria as the major site of medicinal biguanide accumulation within cells

Lei Wang, Xianrong Zeng, Yanjie Li, Wanyu Hao, Zijing Yu, Luxia Yao, Yongdeng Zhang, Zhaobin Wang, Lianfeng Wu

This study uses chemical imaging to show that metformin accumulates primarily in mitochondria within cells.

Heliyon · Jul 1, 2024Peer-reviewedMolecular Biology