Trophectoderm differentiation to invasive syncytiotrophoblast is induced by endometrial epithelial cells during human embryo implantation
Peter T Ruane, Terence Garner, Lydia Parsons, Phoebe A Babbington, Susan J. Kimber, Adam Stevens, Melissa Westwood, Daniel R. Brison, John Aplin
The paper models human embryo implantation using blastocysts and endometrial epithelial cells, showing EEC-induced syncytiotrophoblast differentiation as the mechanism for embryonic invasion.
bioRxiv · Oct 2, 2020 · PreprintDevelopmental Biology