Author

Lyle Curry

University of Cape Town

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Alaine A. MarsdeniD· 1 shared Alec P. PankowiD· 1 shared Allan C. deCampiD· 1 shared Anna YsseliD· 1 shared Asanda Gwashu-Nyangiri· 1 shared Ben MurrelliD· 1 shared Bronwen E. LambsoniD· 1 shared Bryan T. MayeriD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Alaine A. MarsdenORCID

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1 paper

Recent·Most cited

VRC01 Selects Rare HIV Escape Mutations After Acquisition in Antibody-Mediated Prevention Trials

Carolyn E. Williamson, Lyle Curry, Nonhlanhla N. Mkhize, Elena E. Giorgi, Craig A. Magaret, Bronwen E. Lambson, Sinethemba Bhebhe, Haajira Kaldine, Thandeka Moyo-Gwete, Morgane Rolland, Raabya Rossenkhan, Nina Marie G. Garcia, Chivonne Moodley, Anna Yssel, Yunda Huang, , James I. Mullins

This study identifies VRC01-mediated viral escape mutations in HIV-infected participants from antibody-mediated prevention trials, showing that VRC01 can select for escape variants with cross-resistance to other CD4bs bnAbs.

bioRxiv · Oct 29, 2025 · PreprintMicrobiology