Differential activation of G protein-mediated signalling by synthetic cannabinoid receptor agonists
S. Sachdev, S. Banister, M. Santiago, C. Bladen, M. ` Kassiou, M. Connor
This study compares how synthetic cannabinoid receptor agonists activate Gs and Gi/o proteins, finding differences in their potency and rank order for cAMP stimulation and inhibition.
bioRxiv · Nov 22, 2019 · PreprintPharmacology & Toxicology