Oxamniquine resistance alleles are widespread in Old World Schistosoma mansoni and predate drug deployment
F. Chevalier, W. Le Clec'h, M. McDew-White, V. Menon, M. A. Guzman, S. P. Holloway, X. Cao, A. B. Taylor, S. Kinung'hi, A. N. Gouvras, B. L. Webster, J. P. Webster, A. M. Emery, D. Rollinson, A. Garba Djirmay, , T. J. Anderson
The paper identifies widespread oxamniquine resistance alleles in Old World Schistosoma mansoni populations, showing they predate drug use and exist as standing genetic variation.
bioRxiv · Aug 20, 2019Evolutionary Biology