Glioblastoma stem cells induce quiescence in surrounding neural stem cells via Notch signalling
K. Lawlor, M. A. Marques-Torrejon, G. Dharmalingham, Y. El-Azhar, M. D. Schneider, S. M. Pollard, T. A. Rodriguez
The paper shows that glioblastoma stem cells induce quiescence in neighboring neural stem cells through Notch signaling, suggesting a mechanism for oncogenic propagation in the stem cell niche.
bioRxiv · Nov 29, 2019 · PreprintCancer Biology