Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
A. E. P. Loftus, M. S. Romano, A. Nguyen Phuong, M. T. Muir, J. C. Dawson, L. Avalle, A. T. Douglas, R. L. Mort, A. Byron, N. O. Carragher, S. M. Pollard, V. G. Brunton, M. C. Frame
This study identifies a novel ILK-STAT3 pathway that regulates phenotypic plasticity and mesenchymal state in mouse glioblastoma stem cells.
bioRxiv · Jul 19, 2023 · PreprintCancer Biology
S. Lier, S. O. Lund, A. Lipsa, K. B. M. Frauenknecht, I. D. Rein, P. Jain, A. Lang, E. Lang, N. Meyer, A. Datta, S. Anand, G. Nesse, R. J. Forstrom, A. Klungland, J. E. Rinholm, , D. P. Pandey
This study shows that inhibiting CDK12 and CDK13 reduces glioma cell proliferation and migration, and disrupts transcription and cell cycle progression in glioblastoma.
bioRxiv · Jul 14, 2023Cancer Biology
L. J. Brooks, M. P. Clements, J. J. Burden, D. Kocher, L. Richards, S. Castro Devesa, M. Woodberry, M. Ellis, L. Zakka, Z. Jaunmuktane, S. Brandner, G. Morrison, S. M. Pollard, P. B. Dirks, S. Marguerat, S. Parrinello
This study identifies the white matter as a differentiative niche for glioblastomas, showing that tumour cells in contact with it acquire pre-oligodendrocyte-like fate, leading to reduced proliferation and invasion.
bioRxiv · Nov 14, 2020 · PreprintCancer Biology
K. Lawlor, M. A. Marques-Torrejon, G. Dharmalingham, Y. El-Azhar, M. D. Schneider, S. M. Pollard, T. A. Rodriguez
The paper shows that glioblastoma stem cells induce quiescence in neighboring neural stem cells through Notch signaling, suggesting a mechanism for oncogenic propagation in the stem cell niche.
bioRxiv · Nov 29, 2019 · PreprintCancer Biology
P. S. Dewari, B. Southgate, K. Mccarten, G. Monogarov, E. O'Duibhir, N. Quinn, A. Tyrer, C. Plumb, C. Blin, R. Finch, R. B. Bressan, G. Morrison, A. M. Jacobi, M. A. Behlke, A. von Kriegsheim, , S. M. Pollard
The paper introduces an efficient, selection-free, and scalable CRISPR/Cas9-based pipeline for epitope tagging in mammalian stem cells, achieving knock-in efficiencies of 5-30%.
bioRxiv · Jan 29, 2018Cell Biology