BiochemistrybioRxiv
Renal tubule Cpt1a overexpression protects from kidney fibrosis by restoring mitochondrial homeostasis
V. Miguel, J. Tituana, J. I. Herrero…·S. Lamas
This study shows that overexpressing Cpt1a in renal tubular epithelial cells reduces fibrosis by restoring mitochondrial function and bioenergetics in CKD models and human patients.