M. A. Youngblom

Portrait of a generalist bacterium: pathoadaptation, metabolic specialization and extreme environments shape diversity of Staphylococcus saprophyticus

This study characterizes the genetic diversity of Staphylococcus saprophyticus across environments and hosts, identifying a Type VII secretion system linked to bovine mastitis and highlighting the generalist nature of the species.

Adaptation of the Mycobacterium tuberculosis transcriptome to biofilm growth

This study characterizes the transcriptomic adaptation of Mycobacterium tuberculosis to biofilm growth, revealing strain-specific regulatory systems and the role of non-coding RNA in facilitating rapid environmental responses.

Comparative genomics of Streptococcus oralis identifies large scale homologous recombination and a genetic variant associated with infection

This study identifies a genetic variant associated with invasiveness in Streptococcus oralis using genomic data from invasive infections and healthy volunteers.

Rapid adaptation of a complex trait during experimental evolution of Mycobacterium tuberculosis

This study uses experimental evolution of Mycobacterium tuberculosis to identify genetic loci associated with biofilm formation and shows that regulatory mutations rapidly adapt under selective pressure.