Author

M. A. Zafar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Organism:mouse· 4 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. S. Bray· 3 shared T. M. Young· 3 shared A. W. Hudson· 2 shared A. Costa_Terryl· 1 shared A. Hammond· 1 shared A. J. Barnes· 1 shared D. L. Caudell· 1 shared G. Hernandez· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersMicrobiology

A. S. Bray

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Author profile →

5 papers

Recent·Most cited

The two-component system YesMN promotes pneumococcal host-to-host transmission, and regulates genes involved in zinc homeostasis

M. A. Zafar, A. Costa_Terryl, T. M. Young

This study identifies the role of the YesMN two-component system in pneumococcal transmission and zinc homeostasis regulation, showing its importance in coinfection with influenza A virus.

bioRxiv · Aug 29, 2022Microbiology

Klebsiella pneumoniae L-Fucose metabolism promotes gastrointestinal colonization and modulates its virulence determinants

A. W. Hudson, A. J. Barnes, A. S. Bray, M. A. Zafar

This study shows that K. pneumoniae uses fucose metabolism to colonize the gut and modulate its virulence traits, with EcN outcompeting it.

bioRxiv · May 18, 2022Microbiology

MgrB dependent colistin resistance in Klebsiella pneumoniae is associated with an increase in host-to-host transmission.

A. S. Bray, R. D. Smith, A. W. Hudson, G. Hernandez, T. M. Young, R. K. Ernst, M. A. Zafar

This study shows that MgrB-dependent colistin resistance in K. pneumoniae reduces gut colonization but increases survival outside the host, enhancing transmission.

bioRxiv · Dec 1, 2021Microbiology

An Animal Model to Study Klebsiella pneumoniae Gastro-Intestinal Colonization and Host-to-Host Transmission

M. A. Zafar, T. M. Young, A. S. Bray, R. K. Nagpal, D. L. Caudell, H. Yadav

This paper develops a murine model to study Klebsiella pneumoniae gastrointestinal colonization and host-to-host transmission via the fecal-oral route.

bioRxiv · Feb 4, 2020Microbiology

An infant mouse model of influenza virus transmission demonstrates the role of virus-specific shedding, humoral immunity, and sialidase expression by colonizing Streptococcus pneumoniae.

M. B. Ortigoza, S. Blaser, M. A. Zafar, A. Hammond, J. N. Weiser

This paper introduces an infant mouse model to study influenza virus transmission, showing that viral shedding, age, humoral immunity, and sialidase activity of Streptococcus pneumoniae influence transmission efficiency.

bioRxiv · Oct 31, 2018Microbiology