The respiratory virome and exacerbations in patients with chronic obstructive pulmonary disease
A. L. van Rijn, S. van Boheemen, E. C. Carbo, N. Pappas, I. Sidorov, H. Mei, M. Aanerud, P. Bakke, E. C. J. Claas, T. M. Eagan, P. S. Hiemstra, A. C. M. Kroes, J. J. C. de Vries
This study uses metagenomic next-generation sequencing to analyze the respiratory virome in COPD exacerbations, finding high sensitivity and specificity for viral detection and a correlation between viral presence and reduced bacteriophage abundance.
bioRxiv · Jan 2, 2019Microbiology