Author

I. Sidorov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:C. elegans· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metagenomics· 1

Frequent Co-Authors

A. C. M. Kroes· 1 shared A. L. van Rijn· 1 shared B. Spittal· 1 shared C. Harmanus· 1 shared COMBACTE-CDI Consortium· 1 shared E. C. Carbo· 1 shared E. C. J. Claas· 1 shared E. Clark· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperMicrobiology

A. C. M. Kroes

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3 papers

Recent·Most cited

Heme is crucial for medium-dependent metronidazole resistance in clinical isolates of C. difficile

I. M. Boekhoud, I. Sidorov, S. Nooij, C. Harmanus, I. M. J. G. Bos-Sanders, V. Viprey, B. Spittal, E. Clark, K. Davies, J. Freeman, E. J. Kuijper, W. K. Smits, COMBACTE-CDI Consortium, European Study Group for Clostridioides difficile

The paper shows heme dependence in metronidazole resistance in C. difficile clinical isolates, linked to a SNP in hsmA and associated with a resistant lineage.

bioRxiv · Nov 18, 2020Microbiology

SARS-coronavirus-2 replication in Vero E6 cells: replication kinetics, rapid adaptation and cytopathology

N. Ogando, T. Dalebout, J. C. Zevenhoven-Dobbe, R. W. A. L. Limpens, Y. van der Meer, L. Caly, J. Druce, J. de Vries, M. Kikkert, M. Barcena, I. Sidorov, E. J. Snijder

This study compares SARS-CoV-2 and SARS-CoV replication in Vero E6 cells, finding higher viral RNA levels in SARS-CoV-2 but lower infectious progeny, and adaptive mutations in its spike protein.

bioRxiv · Apr 20, 2020Microbiology

The respiratory virome and exacerbations in patients with chronic obstructive pulmonary disease

A. L. van Rijn, S. van Boheemen, E. C. Carbo, N. Pappas, I. Sidorov, H. Mei, M. Aanerud, P. Bakke, E. C. J. Claas, T. M. Eagan, P. S. Hiemstra, A. C. M. Kroes, J. J. C. de Vries

This study uses metagenomic next-generation sequencing to analyze the respiratory virome in COPD exacerbations, finding high sensitivity and specificity for viral detection and a correlation between viral presence and reduced bacteriophage abundance.

bioRxiv · Jan 2, 2019Microbiology