Discovery of specific activity of 2-HPA acting on the membrane progestin receptor α (paqr7) by purification of natural products from the marine algae Padina
M. T. Amin, M. Acharjee, M. M. S. Jyoti, M. Rezanujjaman, M. M. Hassan, M. F. Hossain, S. Ahamed, S. Kodani, T. Tokumoto
This study identifies 2-HPA as a novel mPR antagonist from marine algae Padina arborescens, showing specific inhibitory activity in vitro and in vivo.
bioRxiv · Sep 12, 2023 · PreprintBiochemistry