Cancer BiologybioRxiv
Histone H3K36me2-specific methyltransferase ASH1L is required for the MLL-AF9-induced leukemogenesis
M. B. Aljazi, Y. Gao, Y. Wu…·J. He
This study shows ASH1L's enzymatic activity is essential for MLL-AF9-induced leukemogenesis by enhancing target gene expression through histone modification.
DOI 10.3389/fonc.2021.754093