1-Methyl-tryptophan enantiomers differently affect the cross- talking between mononuclear and tumor cells and interferon-γ production.
M. S. F. Branquinho, M. B. B. Silva, R. O. Clara, A. R. Julio, S. S. M. Engler, E. Pinto Junior, A. Campa
This study shows that D-1-MT enantiomer more effectively inhibits IFN-γ production and enhances PBMC tumoricidal activity compared to L-1-MT in co-cultures with tumor cells.
bioRxiv · Mar 15, 2019 · PreprintPharmacology & Toxicology