Author

A. R. Julio

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:differential expression· 1 Organism:mouse· 1

Frequent Co-Authors

A. B. Ball· 1 shared A. C. Turmon· 1 shared A. Campa· 1 shared A. E. Jones· 1 shared A. S. Divakaruni· 1 shared A. Turmon· 1 shared C. Truong· 1 shared E. Dominguez· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperBiochemistry

A. B. Ball

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Author profile →

3 papers

Recent·Most cited

Pervasive aggregation and depletion of host and viral proteins in response to cysteine-reactive electrophilic compounds

A. R. Julio, F. Shikwana, C. Truong, N. R. Burton, E. Dominguez, A. Turmon, J. Cao, K. Backus

The paper identifies a cysteine-reactive small molecule degrader of SARS-CoV-2 nsp14, showing it causes protein aggregation, depletion, and stress granule formation in cells.

bioRxiv · Oct 30, 2023 · PreprintBiochemistry

Proximity-labeling chemoproteomics defines the subcellular cysteinome and inflammation-responsive mitochondrial redoxome

T. Yan, A. R. Julio, M. Villanueva, A. E. Jones, A. B. Ball, L. M. Boatner, A. C. Turmon, S. L. Yen, H. S. Desai, A. S. Divakaruni, K. M. Backus

The paper develops Cys-LoC and Cys-LOx methods to map compartment-specific cysteine oxidation states, revealing novel mitochondrial redox modifications in response to inflammation.

bioRxiv · Jan 22, 2023Biochemistry

1-Methyl-tryptophan enantiomers differently affect the cross- talking between mononuclear and tumor cells and interferon-γ production.

M. S. F. Branquinho, M. B. B. Silva, R. O. Clara, A. R. Julio, S. S. M. Engler, E. Pinto Junior, A. Campa

This study shows that D-1-MT enantiomer more effectively inhibits IFN-γ production and enhances PBMC tumoricidal activity compared to L-1-MT in co-cultures with tumor cells.

bioRxiv · Mar 15, 2019 · PreprintPharmacology & Toxicology