Endothelial cell flow-mediated quiescence is temporally regulated and utilizes the cell cycle inhibitor p27
N. Tanke, Z. Liu, M. T. Gore, P. Bougaran, M. B. Linares, A. Marvin, A. Sharma, M. Oatley, T. Yu, K. Quigley, S. Vest, J. G. Cook, V. L. Bautch
This study shows that endothelial cell quiescence under flow is temporally regulated and depends on p27, with arterial flow leading to deeper quiescence requiring HES1 and ID3.
bioRxiv · Jun 9, 2023Cell Biology